Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure

Catherine A. Chapin; Thomas M. Burn; Tamir Diamond; Kathleen M. Loomes; Estella M. Alonso; Edward M. Behrens

doi:10.1371/journal.pone.0286394

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Peer-reviewed

Research Article

Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure

Catherine A. Chapin ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

* E-mail: cchapin@luriechildrens.org

Affiliation Department of Pediatrics, Feinberg School of Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University, Chicago, Illinois, United States of America

https://orcid.org/0000-0003-3339-9372

⨯
Thomas M. Burn,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Pediatrics, Perelman School of Medicine, The Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Tamir Diamond,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Pediatrics, Perelman School of Medicine, The Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0002-1904-5351

⨯
Kathleen M. Loomes,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Department of Pediatrics, Perelman School of Medicine, The Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Estella M. Alonso,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – review & editing

Affiliation Department of Pediatrics, Feinberg School of Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University, Chicago, Illinois, United States of America
⨯
Edward M. Behrens

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Department of Pediatrics, Perelman School of Medicine, The Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated T-cell pediatric acute liver failure

Catherine A. Chapin,
Thomas M. Burn,
Tamir Diamond,
Kathleen M. Loomes,
Estella M. Alonso,
Edward M. Behrens

Published: June 2, 2023
https://doi.org/10.1371/journal.pone.0286394

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