Bioassays guided isolation of berberine from Berberis lycium and its neuroprotective role in aluminium chloride induced rat model of Alzheimer’s disease combined with insilico molecular docking

• Hammad Ismail ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: hammad.ismail@uog.edu.pk

  Affiliation Department of Biochemistry and Biotechnology, University of Gujrat, Gujrat, Pakistan

  https://orcid.org/0000-0002-8008-4595

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• Dania Khalid,

  Roles Data curation, Formal analysis, Methodology, Software

  Affiliation Department of Biochemistry and Biotechnology, University of Gujrat, Gujrat, Pakistan

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• Durdana Waseem,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

  Affiliation Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan

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• Muhammad Umar Ijaz,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Zoology, Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan

  https://orcid.org/0000-0002-8398-5364

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• Erum Dilshad,

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Bioinformatics and Biosciences, Faculty of Health and Life Sciences, Capital University of Science and Technology, Islamabad, Pakistan

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• Ihsan-ul Haq,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources

  Affiliation Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan

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• Muhammad Zeeshan Bhatti,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan

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• Sadaf Anwaar,

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Biological Sciences, International Islamic University, Islamabad, Pakistan

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• Madiha Ahmed,

  Roles Formal analysis, Writing – original draft

  Affiliation Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan

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• Samreen Saleem

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Nutrition and Lifestyle Medicine, Health Services Academy, Islamabad, Pakistan

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