Cytotoxic properties of unfractionated and fractionated bromelain alone or in combination with chemotherapeutic agents in colorectal cancer cells

• Kuei-Yen Tsai,

  Roles Conceptualization, Data curation, Investigation, Validation, Writing – original draft

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan

  https://orcid.org/0000-0001-8592-6336

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• Po-Li Wei,

  Roles Conceptualization, Data curation, Project administration, Resources, Software

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of Colorectal Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University, Taipei, Taiwan

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• Mohamed Azarkan,

  Roles Conceptualization, Data curation, Investigation, Resources, Software, Validation, Writing – original draft

  Affiliation Service de Chimie Générale I (CP 609), Faculté de Médicine, Campus Erasme (CP 609), Université Libre de Bruxelles, Brussels, Belgium

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• Nasiha M’Rabet,

  Roles Conceptualization, Investigation, Methodology, Resources

  Affiliation Service de Chimie Générale I (CP 609), Faculté de Médicine, Campus Erasme (CP 609), Université Libre de Bruxelles, Brussels, Belgium

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• Precious Takondwa Makondi,

  Roles Data curation, Investigation, Methodology, Writing – original draft

  Affiliation Kamuzu Central Hospital—National Cancer Center, Lilongwe, Malawi

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• Hsin-An Chen,

  Roles Data curation, Formal analysis, Methodology, Validation, Writing – original draft

  Affiliations Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Division of General Surgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan

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• Chien-Yu Huang ,

  Roles Conceptualization, Methodology, Project administration, Resources, Validation, Writing – original draft

  * E-mail: r5424012@tmu.edu.tw (YJC); cyhuang@life.nthu.edu.tw (CYH)

  Affiliations School of Medicine, National Tsing Hua University, Hsinchu, Taiwan, Institute of Molecular and Cellular Biology, National Tsing Hua University, Hsinchu, Taiwan

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• Yu-Jia Chang

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: r5424012@tmu.edu.tw (YJC); cyhuang@life.nthu.edu.tw (CYH)

  Affiliations Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan, Cancer Research Center, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan

  https://orcid.org/0000-0003-3978-3244

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