The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells

Aubery Henry; Marine Mauperin; Jerome Devy; Stephane Dedieu; Lise Chazee; Cathy Hachet; Christine Terryn; Laurent Duca; Laurent Martiny; Emmanuelle Devarenne-Charpentier; Hassan El Btaouri

doi:10.1371/journal.pone.0285834

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Open Access

Peer-reviewed

Research Article

The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells

Aubery Henry ,

Roles Investigation

¶‡ AH and MM also contributed equally to this work.

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Marine Mauperin ,

Roles Investigation

¶‡ AH and MM also contributed equally to this work.

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Jerome Devy,

Roles Investigation

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Stephane Dedieu,

Roles Investigation

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Lise Chazee,

Roles Investigation

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Cathy Hachet,

Roles Investigation

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Christine Terryn,

Roles Investigation

Affiliation Technical Platform for Cellular and Tissue Imaging (PICT), UFR Pharmacie, URCA, Reims, France
⨯
Laurent Duca,

Roles Investigation

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Laurent Martiny,

Roles Conceptualization, Investigation, Supervision

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Emmanuelle Devarenne-Charpentier ,

Contributed equally to this work with: Emmanuelle Devarenne-Charpentier, Hassan El Btaouri

Roles Investigation, Writing – original draft

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France
⨯
Hassan El Btaouri

Contributed equally to this work with: Emmanuelle Devarenne-Charpentier, Hassan El Btaouri

Roles Conceptualization, Investigation, Project administration, Writing – original draft

* E-mail: hassan.elbtaouri@univ-reims.fr

Affiliation UMR-CNRS 7369 Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UFR SEN, URCA, Reims cedex, France

https://orcid.org/0000-0003-3069-4798

⨯

The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells

Aubery Henry,
Marine Mauperin,
Jerome Devy,
Stephane Dedieu,
Lise Chazee,
Cathy Hachet,
Christine Terryn,
Laurent Duca,
Laurent Martiny,
Emmanuelle Devarenne-Charpentier

Published: September 28, 2023
https://doi.org/10.1371/journal.pone.0285834

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