High rates of kidney impairment among older people (≥ 60 years) living with HIV on first-line antiretroviral therapy at screening for a clinical trial in Kenya

Jeremy Penner; Loice Achieng Ombajo; Davies Otieno; Joseph Nkuranga; Margaret Mburu; Simon Wahome; Anton Pozniak; Sanjay Bhagani

doi:10.1371/journal.pone.0285787

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Open Access

Peer-reviewed

Research Article

High rates of kidney impairment among older people (≥ 60 years) living with HIV on first-line antiretroviral therapy at screening for a clinical trial in Kenya

Jeremy Penner ,

Contributed equally to this work with: Jeremy Penner, Loice Achieng Ombajo

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

* E-mail: pennerja@mail.ubc.ca

Affiliations Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya, Department of Family Practice, University of British Columbia, Vancouver, Canada

https://orcid.org/0000-0001-6443-1748

⨯
Loice Achieng Ombajo ,

Contributed equally to this work with: Jeremy Penner, Loice Achieng Ombajo

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft

Affiliations Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya, Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya
⨯
Davies Otieno,

Roles Writing – review & editing

Affiliation Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya
⨯
Joseph Nkuranga,

Roles Investigation, Supervision, Writing – review & editing

Affiliations Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya, Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya
⨯
Margaret Mburu,

Roles Formal analysis, Writing – review & editing

Affiliation Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya
⨯
Simon Wahome,

Roles Supervision, Writing – review & editing

Affiliation Kenyatta National Hospital, Nairobi, Kenya
⨯
Anton Pozniak,

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Sanjay Bhagani

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Infectious Diseases/HIV Medicine, Royal Free London Foundation Trust, London, United Kingdom
⨯

High rates of kidney impairment among older people (≥ 60 years) living with HIV on first-line antiretroviral therapy at screening for a clinical trial in Kenya

Jeremy Penner,
Loice Achieng Ombajo,
Davies Otieno,
Joseph Nkuranga,
Margaret Mburu,
Simon Wahome,
Anton Pozniak,
Sanjay Bhagani

Published: June 23, 2023
https://doi.org/10.1371/journal.pone.0285787

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Kidneys
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Kenya
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Chronic kidney disease
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Antiretroviral therapy
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Geriatric care
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Protease inhibitor therapy
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Creatinine
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HIV
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