Development of a method of passaging and freezing human iPS cell-derived hepatocytes to improve their functions

• Jumpei Inui,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

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• Yukiko Ueyama-Toba,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliations Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, Laboratory of Functional Organoid for Drug Discovery, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, Japan, Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan

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• Seiji Mitani,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Current address: Advanced Medical Science of Thrombosis and Hemostasis, Nara Medical University, Nara, Japan

  Affiliation Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan

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• Hiroyuki Mizuguchi

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mizuguch@phs.osaka-u.ac.jp

  Affiliations Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan, Laboratory of Functional Organoid for Drug Discovery, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, Japan, Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan, Global Center for Medical Engineering and Informatics, Osaka University, Osaka, Japan, Center for Infectious Disease Education and Research (CiDER), Osaka University, Osaka, Japan

  https://orcid.org/0000-0003-0594-8178

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