Tetra-O-methyl-nordihydroguaiaretic acid inhibits energy metabolism and synergistically induces anticancer effects with temozolomide on LN229 glioblastoma tumors implanted in mice while preventing obesity in normal mice that consume high-fat diets

• Kotohiko Kimura,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Jong Ho Chun,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Yu-Ling Lin,

  Roles Data curation, Investigation

  Affiliation Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan, Republic of China

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• Yu-Chuan Liang,

  Roles Data curation, Investigation

  Affiliation Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan, Republic of China

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• Tiffany L. B. Jackson,

  Roles Data curation, Investigation, Software, Writing – review & editing

  Affiliation Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0002-0800-1484

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• Ru Chih C. Huang

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rhuang@jhu.edu

  Affiliations Department of Biology, Johns Hopkins University, Baltimore, Maryland, United States of America, Academician, Academia Sinica, Taipei, Taiwan, Republic of China

  https://orcid.org/0000-0001-5650-2657

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