Efficacy and safety of Mojeaga remedy in combination with conventional oral iron therapy for correcting anemia in obstetric population: A phase II randomized pilot clinical trial

• George Uchenna Eleje ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: georgel21@yahoo.com, gu.eleje@unizik.edu.ng

  Affiliations Effective care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi, Nigeria, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  https://orcid.org/0000-0002-0390-2152

  ⨯
• Ifeanyichukwu Uzoma Ezebialu,

  Roles Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria

  ⨯
• Joseph Tochukwu Enebe,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Nnanyelugo Chima Ezeora,

  Roles Data curation, Formal analysis, Investigation, Project administration, Resources, Visualization, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Emmanuel Onyebuchi Ugwu,

  Roles Formal analysis, Methodology, Project administration, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Ituku-Ozalla, Enugu, Nigeria

  https://orcid.org/0000-0002-3342-434X

  ⨯
• Iffiyeosuo Dennis Ake,

  Roles Data curation, Funding acquisition, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliation Clinical Trial Division, Drug Evaluation and Research Directorate, NAFDAC, Lagos, Nigeria

  ⨯
• Ekeuda Uchenna Nwankwo,

  Roles Formal analysis, Funding acquisition, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Rural Community Clinical School, School of Medicine, Deakin University, Victoria, Australia

  ⨯
• Perpetua Kelechi Enyinna ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Chukwuemeka Chukwubuikem Okoro ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  https://orcid.org/0000-0001-5772-661X

  ⨯
• Chika Prince Asuoha ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemical Pathology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria

  ⨯
• Charlotte Blanche Oguejiofor ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Ejeatuluchukwu Obi,

  Roles Investigation, Methodology, Project administration, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology and Therapeutics, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Chigozie Geoffrey Okafor ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  https://orcid.org/0000-0003-4458-8216

  ⨯
• Angela Ogechukwu Ugwu ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Haematology and Immunology, College of Medicine, University of Nigeria Ituku-Ozalla, Enugu, Nigeria

  ⨯
• Lydia Ijeoma Eleje ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Measurement, Evaluation and Research Unit, Department of Educational Foundations, Nnamdi Azikiwe University, Awka, Nigeria

  ⨯
• Divinefavour Echezona Malachy ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Effective care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Chukwunonso Emmanuel Ubammadu,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Effective care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Emeka Philip Igbodike,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Chidebe Christian Anikwe ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Ifeoma Clara Ajuba ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Haematology, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Chinyelu Uchenna Ufoaroh,

  Roles Data curation, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Richard Obinwanne Egeonu ,

  Roles Formal analysis, Investigation, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Lazarus Ugochukwu Okafor,

  Roles Data curation, Formal analysis, Investigation, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Chukwunonso Isaiah Enechukwu,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Sussan Ifeyinwa Nweje ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Nursing, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria

  ⨯
• Onyedika Promise Anaedu ,

  Roles Data curation, Formal analysis, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Odigonma Zinobia Ikpeze ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Boniface Chukwuneme Okpala ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Methodology, Project administration, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliations Effective care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi, Nigeria, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Ekene Agatha Emeka ,

  Roles Data curation, Formal analysis, Investigation, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Family Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria

  ⨯
• Chijioke Stanley Nzeukwu,

  Roles Data curation, Funding acquisition, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria

  https://orcid.org/0000-0003-1676-5721

  ⨯
• Ifeanyi Chibueze Aniedu ,

  Contributed equally to this work with: Perpetua Kelechi Enyinna, Chukwuemeka Chukwubuikem Okoro, Chika Prince Asuoha, Charlotte Blanche Oguejiofor, Chigozie Geoffrey Okafor, Angela Ogechukwu Ugwu, Lydia Ijeoma Eleje, Chidebe Christian Anikwe, Ifeoma Clara Ajuba, Sussan Ifeyinwa Nweje, Boniface Chukwuneme Okpala, Ifeanyi Chibueze Aniedu

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria

  ⨯
• Emmanuel Chidi Chukwuka,

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, Awka, Nigeria

  ⨯
• Arinze Anthony Onwuegbuna,

  Roles Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Ophthalmology, Nnamdi Azikiwe University, Awka, Nigeria

  ⨯
• David Chibuike Ikwuka ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Human Physiology, Nnamdi Azikiwe University, Nnewi, Anambra State, Nigeria

  https://orcid.org/0000-0002-1465-7033

  ⨯
• Chisom God’swill Chigbo,

  Roles Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Executive MPH, School of Public Health, University of Port-Harcourt, Port-Harcourt, Rivers State, Nigeria

  ⨯
• Chiemezie Mac-Kingsley Agbanu ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Chidinma Ifechi Onwuka,

  Roles Data curation, Formal analysis, Investigation, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria Ituku-Ozalla, Enugu, Nigeria

  ⨯
• Malarchy Ekwunife Nwankwo ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Henry Chinedu Nneji,

  Roles Data curation, Formal analysis, Investigation, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
• Kosisochukwu Amarachukwu Onyeukwu,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  https://orcid.org/0000-0001-8684-8069

  ⨯
• Boniface Uwaezuoke Odugu,

  Roles Data curation, Formal analysis, Investigation, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Sylvester Onuegbunam Nweze,

  Roles Data curation, Formal analysis, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Ifeanyi Johnson Onyekpa,

  Roles Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Obstetrics and Gynecology, ESUT Teaching Hospital, Parklane, Enugu, Nigeria

  ⨯
• Kenneth Chukwudi Eze ,

  Roles Data curation, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Radiology, Faculty of Medicine, College of Health Sciences, Nnamdi Azikiwe University, Awka, Nigeria

  https://orcid.org/0000-0001-6346-2905

  ⨯
• Shirley Nneka Chukwurah ,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Internal Medicine, Faculty of Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

  ⨯
• Joseph Odirichukwu Ugboaja ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ DEM, ROE, OPA, OZI, EAE, DCI, CMKA, MEN, KCE, SNC and JOU also contributed equally to this work.

  Affiliation Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

  ⨯
•  [ ... ],
• Joseph Ifeanyichukwu Ikechebelu

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Effective care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi, Nigeria, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital Nnewi, Nnewi, Anambra State, Nigeria

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