Integrated brain and plasma dual-channel metabolomics to explore the treatment effects of Alpinia oxyphyllaFructus on Alzheimer’s disease

• Zhi Sun ,

  Contributed equally to this work with: Zhi Sun, Yuanyuan Zhang

  Roles Conceptualization, Project administration, Writing – review & editing

  * E-mail: sunzhi2013@163.com

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

  https://orcid.org/0000-0001-6007-4923

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• Yuanyuan Zhang ,

  Contributed equally to this work with: Zhi Sun, Yuanyuan Zhang

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Mengya Zhang,

  Roles Data curation, Writing – original draft

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Shengnan Zhou,

  Roles Data curation, Methodology

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Wenbo Cheng,

  Roles Investigation, Supervision

  Affiliation Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China

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• Lianping Xue,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Peipei Zhou,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Xiaojing Li,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Zhibo Zhang,

  Roles Data curation, Writing – original draft

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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• Lihua Zuo

  Roles Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China, Henan Engineering Research Center of Clinical Mass Spectrometry for Precision Medicine, Zhengzhou, Henan Province, China

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