A single-dose, randomized crossover study in healthy Chinese subjects to evaluate pharmacokinetics and bioequivalence of two capsules of calcium dobesilate 0.5 g under fasting and fed conditions

• Yanmei Liu,

  Roles Investigation, Project administration, Supervision, Writing – review & editing

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Jie Cheng,

  Roles Investigation

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Liyu Liang,

  Roles Writing – original draft, Writing – review & editing

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Weigang Qian,

  Roles Methodology, Resources

  Affiliation Shanghai Zhaohui Pharmaceutical Co., Ltd., Shanghai, China

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• Meixian Ou,

  Roles Project administration, Validation

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Mengqi Zhang,

  Roles Methodology, Project administration, Validation

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Yijun Wang,

  Roles Investigation, Project administration

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

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• Yan Wang,

  Roles Methodology, Resources

  Affiliation Shanghai Zhaohui Pharmaceutical Co., Ltd., Shanghai, China

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• Ka Peng ,

  Roles Funding acquisition, Project administration

  * E-mail: pengka001@163.com (KP); jyjia@shxh-centerlab.com (JJ)

  Affiliation Shanghai Center of Biomedicine Development, Shanghai, China

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• Jingying Jia

  Roles Investigation, Methodology, Project administration, Supervision

  * E-mail: pengka001@163.com (KP); jyjia@shxh-centerlab.com (JJ)

  Affiliations Central Laboratory, Shanghai Xuhui Central Hospital, Shanghai, China, Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs, Shanghai, China

  https://orcid.org/0000-0002-2492-3219

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