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Open Access

Peer-reviewed

Research Article

Characterization of multivalent complexes formed in the presence of more than one conventional antibody to terminal complement component C5

Josh Cone,

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Alexion, AstraZeneca Rare Disease, New Haven, CT, United States of America
⨯
Lida Kimmel,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Alexion Pharmaceuticals, Inc., New Haven, CT, United States of America
⨯
Yuchun Zhang,

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Alexion, AstraZeneca Rare Disease, New Haven, CT, United States of America
⨯
Krista Johnson,

Roles Formal analysis, Supervision, Writing – review & editing

Affiliation Alexion, AstraZeneca Rare Disease, New Haven, CT, United States of America
⨯
Douglas Sheridan,

Roles Conceptualization, Formal analysis, Writing – review & editing

Affiliation Alexion Pharmaceuticals, Inc., New Haven, CT, United States of America
⨯
Paul Tamburini

Roles Conceptualization, Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: paul.tamburini@alexion.com

Affiliation Alexion, AstraZeneca Rare Disease, New Haven, CT, United States of America

https://orcid.org/0000-0003-3187-2314

⨯

Characterization of multivalent complexes formed in the presence of more than one conventional antibody to terminal complement component C5

Josh Cone,
Lida Kimmel,
Yuchun Zhang,
Krista Johnson,
Douglas Sheridan,
Paul Tamburini

x

Published: April 20, 2023
https://doi.org/10.1371/journal.pone.0284502

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Complement system
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Blood plasma
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Enzyme-linked immunoassays
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Immune complex
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Monoclonal antibodies
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