Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism

Zander Harpel; Wei-Jen Chang; Jacob Circelli; Richard Chen; Ian Chang; Jason Rivera; Stephanie Wu; RongHan Wei

doi:10.1371/journal.pone.0284309

Loading metrics

Open Access

Peer-reviewed

Research Article

Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism

Zander Harpel ,

Contributed equally to this work with: Zander Harpel, Wei-Jen Chang

Roles Formal analysis, Investigation, Software, Writing – original draft

Affiliation Department of Biology, Hamilton College, Clinton, NY, United States of America
⨯
Wei-Jen Chang ,

Contributed equally to this work with: Zander Harpel, Wei-Jen Chang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

* E-mail: wchang@hamilton.edu (WJC); profwei@zzu.edu.cn (RW)

Affiliation Department of Biology, Hamilton College, Clinton, NY, United States of America

https://orcid.org/0000-0002-8065-2281

⨯
Jacob Circelli,

Roles Data curation, Investigation

Affiliation Department of Biology, Hamilton College, Clinton, NY, United States of America
⨯
Richard Chen,

Roles Data curation, Investigation

Affiliation College of Literature, Science, and Arts, University of Michigan, Ann Arbor, MI, United States of America
⨯
Ian Chang,

Roles Data curation, Investigation

Affiliation Clinton Senior High School, Clinton, NY, United States of America
⨯
Jason Rivera,

Roles Data curation, Investigation

Affiliation Clinton Senior High School, Clinton, NY, United States of America
⨯
Stephanie Wu,

Roles Data curation, Investigation

Affiliation Department of Biology, Hamilton College, Clinton, NY, United States of America
⨯
RongHan Wei

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

* E-mail: wchang@hamilton.edu (WJC); profwei@zzu.edu.cn (RW)

Affiliation Engineering Technology Research Center of Henan Province for MEMS Manufacturing and Applications, School of Mechanics and Safety Engineering, Zhengzhou University, Zhengzhou, Henan, China
⨯

Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism

Zander Harpel,
Wei-Jen Chang,
Jacob Circelli,
Richard Chen,
Ian Chang,
Jason Rivera,
Stephanie Wu,
RongHan Wei

Published: September 14, 2023
https://doi.org/10.1371/journal.pone.0284309

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Tetrahymena thermophila
Is the Subject Area "Tetrahymena thermophila" applicable to this article?

Thanks for your feedback.
Pyrimidines
Is the Subject Area "Pyrimidines" applicable to this article?

Thanks for your feedback.
Uridine
Is the Subject Area "Uridine" applicable to this article?

Thanks for your feedback.
Thymidines
Is the Subject Area "Thymidines" applicable to this article?

Thanks for your feedback.
Uracils
Is the Subject Area "Uracils" applicable to this article?

Thanks for your feedback.
Tetrahymena
Is the Subject Area "Tetrahymena" applicable to this article?

Thanks for your feedback.
Nucleosides
Is the Subject Area "Nucleosides" applicable to this article?

Thanks for your feedback.
Thymine
Is the Subject Area "Thymine" applicable to this article?

Thanks for your feedback.