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Open Access

Peer-reviewed

Research Article

Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway

Fei Yang,

Roles Writing – original draft

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Jie Zhang,

Roles Data curation

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Zhijun Zhao,

Roles Data curation

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Yan Liu,

Roles Data curation

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Zhen Zhao,

Roles Data curation

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Kai Fu,

Roles Data curation

Affiliation Department of Otolaryngology Head and Neck Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Baokun Li,

Roles Data curation

Affiliation The Second General Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China
⨯
Jing Jin

Roles Writing – original draft

* E-mail: 416057233@qq.com

Affiliation Cancer Institute, Fourth Hospital of Hebei Medical University, Shijiazhuang, China

https://orcid.org/0000-0002-5346-1543

⨯

Artemisinin suppresses aerobic glycolysis in thyroid cancer cells by downregulating HIF-1a, which is increased by the XIST/miR-93/HIF-1a pathway

Fei Yang,
Jie Zhang,
Zhijun Zhao,
Yan Liu,
Zhen Zhao,
Kai Fu,
Baokun Li,
Jing Jin

x

Published: April 10, 2023
https://doi.org/10.1371/journal.pone.0284242

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Glycolysis
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Artemisinin
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Thyroid carcinoma
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Metastasis
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Cell binding assay
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Cell cycle and cell division
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Cell cycle inhibitors
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Luciferase assay
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