Effectiveness of nirmatrelvir-ritonavir for the treatment of patients with mild to moderate COVID-19 and at high risk of hospitalization: Systematic review and meta-analyses of observational studies

• Kathiaja Miranda Souza ,

  Contributed equally to this work with: Kathiaja Miranda Souza, Gabriela Carrasco, Mariana Michel Barbosa

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Independent Consultant, Belo Horizonte, Brazil

  https://orcid.org/0000-0002-9054-4794

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• Gabriela Carrasco ,

  Contributed equally to this work with: Kathiaja Miranda Souza, Gabriela Carrasco, Mariana Michel Barbosa

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: gabi_carrasco@hotmail.com

  Affiliation Red Argentina Pública de Evaluación de Tecnologías Sanitarias (REDARETS), Neuquén, Argentina

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• Robin Rojas-Cortés ,

  Roles Conceptualization, Supervision, Validation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliation Department of Health Systems and Services, Pan American Health Organization, Unit of Medicines and Health Technologies, Washington, DC, United States of America

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• Mariana Michel Barbosa ,

  Contributed equally to this work with: Kathiaja Miranda Souza, Gabriela Carrasco, Mariana Michel Barbosa

  Roles Conceptualization, Data curation, Formal analysis, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Postgraduate Program in Medicines and Pharmaceutical Services, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Eduardo Henrique Ferreira Bambirra ,

  Roles Formal analysis, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliation Postgraduate Program in Medicines and Pharmaceutical Services, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  https://orcid.org/0000-0002-1590-8500

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• José Luis Castro ,

  Roles Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliation Fundación Para la Innovación, la Formación, la Investigación y el Desarrollo Comunitário (FÜNDEC), San Isidro, S/C de Tenerife, España

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• Juliana Alvares-Teodoro

  Roles Conceptualization, Formal analysis, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work

  Affiliations Postgraduate Program in Medicines and Pharmaceutical Services, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, Faculty of Pharmacy, Department of Social Pharmacy, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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