Identifying multivariate disease trajectories and potential phenotypes of early knee osteoarthritis in the CHECK cohort

Sara Altamirano; Mylène P. Jansen; Daniel L. Oberski; Marinus J. C. Eijkemans; Simon C. Mastbergen; Floris P. J. G. Lafeber; Willem E. van Spil; Paco M. J. Welsing

doi:10.1371/journal.pone.0283717

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Open Access

Peer-reviewed

Research Article

Identifying multivariate disease trajectories and potential phenotypes of early knee osteoarthritis in the CHECK cohort

Sara Altamirano,

Roles Data curation, Formal analysis, Project administration, Visualization, Writing – original draft

Affiliation Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Mylène P. Jansen ,

Roles Data curation, Formal analysis, Project administration, Writing – original draft

* E-mail: m.p.jansen-36@umcutrecht.nl

Affiliation Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

https://orcid.org/0000-0003-1929-6350

⨯
Daniel L. Oberski,

Roles Formal analysis, Supervision, Visualization, Writing – review & editing

Affiliations Department of Methodology and Statistics, Faculty of Social and Behavioral Sciences, Utrecht University, Utrecht, the Netherlands, Department of Data Science and Biostatistics, Julius Center, University Medical Center Utrecht, Utrecht, the Netherlands
⨯
Marinus J. C. Eijkemans,

Roles Formal analysis, Investigation, Supervision, Writing – review & editing

Affiliation Department of Data Science and Biostatistics, Julius Center, University Medical Center Utrecht, Utrecht, the Netherlands
⨯
Simon C. Mastbergen,

Roles Formal analysis, Investigation, Supervision, Writing – review & editing

Affiliation Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Floris P. J. G. Lafeber,

Roles Formal analysis, Investigation, Supervision, Writing – review & editing

Affiliation Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Willem E. van Spil,

Roles Conceptualization, Formal analysis, Investigation, Supervision, Writing – review & editing

Affiliations Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Rheumatology, Dijklander Hospital, Hoorn, The Netherlands

https://orcid.org/0000-0002-4980-5630

⨯
Paco M. J. Welsing

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
⨯

Identifying multivariate disease trajectories and potential phenotypes of early knee osteoarthritis in the CHECK cohort

Sara Altamirano,
Mylène P. Jansen,
Daniel L. Oberski,
Marinus J. C. Eijkemans,
Simon C. Mastbergen,
Floris P. J. G. Lafeber,
Willem E. van Spil,
Paco M. J. Welsing

Published: July 14, 2023
https://doi.org/10.1371/journal.pone.0283717

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Osteoarthritis
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Pain
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