Non-invasive and objective tear film breakup detection on interference color images using convolutional neural networks

• Yasushi Kikukawa ,

  Contributed equally to this work with: Yasushi Kikukawa, Shin Tanaka

  Roles Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft

  * E-mail: ykikukawa@kowa.com

  Affiliation Kowa Ophthalmic Research Laboratories, Kowa Research Institute, Inc., Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-1964-5496

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• Shin Tanaka ,

  Contributed equally to this work with: Yasushi Kikukawa, Shin Tanaka

  Roles Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – review & editing

  Affiliation Kowa Company, Ltd., Tokyo, Japan

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• Takuya Kosugi,

  Roles Conceptualization, Data curation, Project administration, Writing – review & editing

  Affiliation Kowa Ophthalmic Research Laboratories, Kowa Research Institute, Inc., Boston, Massachusetts, United States of America

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• Stephen C. Pflugfelder

  Roles Investigation, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, United States of America

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