Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn ^R493X mouse model of frontotemporal dementia

• Denise M. Smith,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Institute for Translational Neuroscience, Saint Louis University, St. Louis, Missouri, United States of America

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• Michael L. Niehoff,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Veterans Affairs Medical Center, St. Louis, Missouri, United States of America

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• Karen Ling,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Ionis Pharmaceuticals, Carlsbad, California, United States of America

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• Paymaan Jafar-Nejad,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Ionis Pharmaceuticals, Carlsbad, California, United States of America

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• Frank Rigo,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Ionis Pharmaceuticals, Carlsbad, California, United States of America

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• Susan A. Farr,

  Roles Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Institute for Translational Neuroscience, Saint Louis University, St. Louis, Missouri, United States of America, Veterans Affairs Medical Center, St. Louis, Missouri, United States of America

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• Miles F. Wilkinson,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, California, United States of America, Institute of Genomic Medicine, University of California San Diego, La Jolla, California, United States of America

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• Andrew D. Nguyen

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: andy.d.nguyen@health.slu.edu

  Affiliations Division of Geriatric Medicine, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Department of Pharmacology and Physiology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America, Institute for Translational Neuroscience, Saint Louis University, St. Louis, Missouri, United States of America

  https://orcid.org/0000-0002-9492-9472

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