Amino acid substitutions in human growth hormone affect secondary structure and receptor binding

• Andrei Rajkovic,

  Roles Investigation

  Affiliation Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

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• Sandesh Kanchugal,

  Roles Methodology, Supervision

  Affiliation Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

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• Eldar Abdurakhmanov,

  Roles Methodology

  Affiliation Department of Chemistry, Uppsala University, Uppsala, Sweden

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• Rebecca Howard,

  Roles Methodology

  Affiliation Department of Biochemistry and Biophysics, Stockholm University, Frescati, Sweden

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• Sebastian Wärmländer,

  Roles Methodology

  Affiliation Department of Biochemistry and Biophysics, Stockholm University, Frescati, Sweden

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• Joseph Erwin,

  Roles Investigation

  Affiliation Department of Biochemistry and Biophysics, Stockholm University, Frescati, Sweden

  https://orcid.org/0000-0002-5023-4177

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• Hugo A. Barrera Saldaña,

  Roles Writing – review & editing

  Affiliation Department of Biochemistry, Autonomous University of Nuevo León, Monterrey, Mexico

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• Astrid Gräslund,

  Roles Methodology, Supervision

  Affiliation Department of Biochemistry and Biophysics, Stockholm University, Frescati, Sweden

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• Helena Danielson,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Chemistry, Uppsala University, Uppsala, Sweden

  https://orcid.org/0000-0003-2728-0340

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• Samuel Coulbourn Flores

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: samuel.flores@slu.se

  Affiliations Department of Biochemistry and Biophysics, Stockholm University, Frescati, Sweden, Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden

  https://orcid.org/0000-0002-3869-8147

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