Oxidative stress, dysfunctional energy metabolism, and destabilizing neurotransmitters altered the cerebral metabolic profile in a rat model of simulated heliox saturation diving to 4.0 MPa

• Xia Liu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Yiqun Fang ,

  Roles Conceptualization, Writing – review & editing

  * E-mail: 1287225836@qq.com (YF); 1574006873@qq.com (CL)

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Jiajun Xu,

  Roles Validation

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Tao Yang,

  Roles Data curation, Supervision

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Ji Xu,

  Roles Data curation, Methodology, Supervision

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Jia He,

  Roles Investigation, Methodology, Visualization

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Wenwu Liu,

  Roles Investigation, Supervision

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Xuhua Yu,

  Roles Investigation, Supervision

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Yukun Wen,

  Roles Investigation, Validation

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

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• Naixia Zhang,

  Roles Supervision

  Affiliation Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Ci Li

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: 1287225836@qq.com (YF); 1574006873@qq.com (CL)

  Affiliation Department of Diving and Hyperbaric Medicine, Navy Medical Center of PLA, Naval Medical University (Second Military Medical University), Shanghai, China

  https://orcid.org/0000-0002-9572-1155

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