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Open Access

Peer-reviewed

Research Article

How important are concurrent vehicle control groups in (sub)chronic non-human primate toxicity studies conducted in pharmaceutical development? An opportunity to reduce animal numbers

Lars Mecklenburg ,

Roles Conceptualization, Data curation, Supervision, Writing – review & editing

* E-mail: lars.mecklenburg@labcorp.com

Affiliation Labcorp Early Development Services GmbH, Muenster, Germany

https://orcid.org/0000-0002-9775-1649

⨯
Sarah Lenz,

Roles Data curation, Formal analysis, Writing – original draft

Affiliations Labcorp Early Development Services GmbH, Muenster, Germany, Institute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms University, Muenster, Germany
⨯
Georg Hempel

Roles Conceptualization, Supervision

Affiliation Institute for Pharmaceutical and Medicinal Chemistry, Westphalian Wilhelms University, Muenster, Germany
⨯

How important are concurrent vehicle control groups in (sub)chronic non-human primate toxicity studies conducted in pharmaceutical development? An opportunity to reduce animal numbers

Lars Mecklenburg,
Sarah Lenz,
Georg Hempel

x

Published: August 3, 2023
https://doi.org/10.1371/journal.pone.0282404
See the preprint

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