Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation

Zhao Liu; Mengjie Liu; Gongwei Jia; Jiani Li; Lingchuan Niu; Huiji Zhang; Yunwen Qi; Houchao Sun; Liang-Jun Yan; Jingxi Ma

doi:10.1371/journal.pone.0282338

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Open Access

Peer-reviewed

Research Article

Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation

Zhao Liu,

Roles Methodology

Affiliations Department of Neurology, Chongqing General Hospital, Chongqing, China, Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China
⨯
Mengjie Liu,

Roles Methodology

Affiliation Department of Neurology, People’s Hospital of Chongqing Banan District, Chongqing, China
⨯
Gongwei Jia,

Roles Methodology

Affiliation Department of Rehabilitation, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
⨯
Jiani Li,

Roles Methodology

Affiliation Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
⨯
Lingchuan Niu,

Roles Methodology

Affiliation Department of Rehabilitation, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
⨯
Huiji Zhang,

Roles Methodology

Affiliations Department of Neurology, Chongqing General Hospital, Chongqing, China, Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China
⨯
Yunwen Qi,

Roles Data curation

Affiliations Department of Neurology, Chongqing General Hospital, Chongqing, China, Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China
⨯
Houchao Sun,

Roles Data curation, Writing – original draft

Affiliations Department of Neurology, Chongqing General Hospital, Chongqing, China, Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China
⨯
Liang-Jun Yan,

Roles Writing – review & editing

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of North Texas Health Science Center, Fort Worth, TX, United States of America

https://orcid.org/0000-0002-5815-5430

⨯
Jingxi Ma

Roles Conceptualization

* E-mail: majingxi@ucas.ac.cn

Affiliations Department of Neurology, Chongqing General Hospital, Chongqing, China, Chongqing Key Laboratory of Neurodegenerative Diseases, Chongqing, China

https://orcid.org/0000-0001-9189-4684

⨯

Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation

Zhao Liu,
Mengjie Liu,
Gongwei Jia,
Jiani Li,
Lingchuan Niu,
Huiji Zhang,
Yunwen Qi,
Houchao Sun,
Liang-Jun Yan,
Jingxi Ma

Published: March 30, 2023
https://doi.org/10.1371/journal.pone.0282338

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Diet
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Ischemic stroke
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Neurological signaling
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