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Open Access
Peer-reviewed
Research Article
Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score
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Aaron P. Thrift ,
Roles Conceptualization, Investigation, Methodology, Writing – original draft
* E-mail: aaron.thrift@bcm.edu (APT); hasheme@bcm.edu (HBES)
Affiliations Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, United States of America
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Fasiha Kanwal,
Roles Funding acquisition, Investigation, Writing – review & editing
Affiliations Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, United States of America
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Yanhong Liu,
Roles Formal analysis, Methodology, Writing – review & editing
Affiliations Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, United States of America
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Saira Khaderi,
Roles Data curation, Writing – review & editing
Affiliation Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Amit G. Singal,
Roles Data curation, Funding acquisition, Writing – review & editing
Affiliation Division of Digestive and Liver Diseases, Department of Medicine, UT Southwestern Medical Center, Dallas, Texas, United States of America
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Jorge A. Marrero,
Roles Data curation, Writing – review & editing
Affiliation Division of Digestive and Liver Diseases, Department of Medicine, UT Southwestern Medical Center, Dallas, Texas, United States of America
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Nicole Loo,
Roles Data curation, Writing – review & editing
Affiliation Texas Liver Institute, San Antonio, Texas, United States of America
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Sumeet K. Asrani,
Roles Data curation, Writing – review & editing
Affiliation Baylor University Medical Center, Dallas, Texas, United States of America
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Michelle Luster,
Roles Project administration, Writing – review & editing
Affiliation Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Abeer Al-Sarraj,
Roles Data curation, Project administration, Writing – review & editing
Affiliations Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, United States of America
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Jing Ning,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Department of Biostatistics, UT MD Anderson Cancer Center, Houston, Texas, United States of America
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Spiridon Tsavachidis,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Xiangjun Gu,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Christopher I. Amos,
Roles Conceptualization, Methodology, Writing – review & editing
Affiliations Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, United States of America
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Hashem B. El-Serag
Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing
* E-mail: aaron.thrift@bcm.edu (APT); hasheme@bcm.edu (HBES)
Affiliations Section of Gastroenterology and Hepatology, Department of Medicine, Baylor College of Medicine, Houston, TX, United States of America, Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, United States of America
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Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score
- Aaron P. Thrift,
- Fasiha Kanwal,
- Yanhong Liu,
- Saira Khaderi,
- Amit G. Singal,
- Jorge A. Marrero,
- Nicole Loo,
- Sumeet K. Asrani,
- Michelle Luster,
- Abeer Al-Sarraj
- Published: February 28, 2023
- https://doi.org/10.1371/journal.pone.0282309