Is retina affected in Huntington’s disease? Is optical coherence tomography a good biomarker?

Pavel Dusek; Ales Kopal; Michaela Brichova; Jan Roth; Olga Ulmanova; Jiri Klempir; Jana Lizrova Preiningerova

doi:10.1371/journal.pone.0282175

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Open Access

Peer-reviewed

Research Article

Is retina affected in Huntington’s disease? Is optical coherence tomography a good biomarker?

Pavel Dusek ,

Contributed equally to this work with: Pavel Dusek, Ales Kopal

Roles Data curation, Formal analysis, Software, Writing – review & editing

Affiliation Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic

https://orcid.org/0000-0003-4307-8206

⨯
Ales Kopal ,

Contributed equally to this work with: Pavel Dusek, Ales Kopal

Roles Data curation, Investigation, Writing – original draft

Affiliations Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic, Department of Neurology, Regional Hospital Pardubice, Pardubice, Czech Republic
⨯
Michaela Brichova,

Roles Investigation

Affiliation Department of Ophthalmology, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
⨯
Jan Roth,

Roles Conceptualization, Methodology, Project administration, Supervision

Affiliation Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
⨯
Olga Ulmanova,

Roles Investigation

Affiliation Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
⨯
Jiri Klempir,

Roles Funding acquisition, Investigation

Affiliation Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
⨯
Jana Lizrova Preiningerova

Roles Conceptualization, Data curation, Investigation, Methodology, Supervision

* E-mail: jana.lizrova@vfn.cz

Affiliation Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic
⨯

Is retina affected in Huntington’s disease? Is optical coherence tomography a good biomarker?

Pavel Dusek,
Ales Kopal,
Michaela Brichova,
Jan Roth,
Olga Ulmanova,
Jiri Klempir,
Jana Lizrova Preiningerova

Published: February 24, 2023
https://doi.org/10.1371/journal.pone.0282175

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Huntington disease
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Tomography
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Retina
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Tobacco mosaic virus
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Cognition
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Color vision
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Visual impairments
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Nerve fibers
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