Novel Bruton’s tyrosine kinase inhibitor TAS5315 suppresses the progression of inflammation and joint destruction in rodent collagen-induced arthritis

• Daichi Akasaka ,

  Roles Investigation, Validation, Visualization, Writing – original draft

  * E-mail: d-akasaka@taiho.co.jp

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

  https://orcid.org/0000-0002-2786-9406

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• Satoru Iguchi ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Ryusuke Kaneko ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Yohei Yoshiga ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Data curation, Investigation, Project administration, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Daisuke Kajiwara ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Yoshinori Nakachi ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Naruto Noma ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Kenji Tanaka ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Atsushi Shimizu ,

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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• Fumihito Hosoi

  Contributed equally to this work with: Satoru Iguchi, Ryusuke Kaneko, Yohei Yoshiga, Daisuke Kajiwara, Yoshinori Nakachi, Naruto Noma, Kenji Tanaka, Atsushi Shimizu, Fumihito Hosoi

  Roles Conceptualization, Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Discovery and Preclinical Research Division, Taiho Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan

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