A novel integrative multi-omics approach to unravel the genetic determinants of rare diseases with application in sinusoidal obstruction syndrome

• Nicolas Waespe ,

  Contributed equally to this work with: Nicolas Waespe, Simona Jurkovic Mlakar

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Institute of Social and Preventive Medicine, Childhood Cancer Research Group, University of Bern, Bern, Switzerland, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, CANSEARCH Research Platform in Pediatric Oncology and Hematology, University of Geneva, Geneva, Switzerland, Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland

  https://orcid.org/0000-0002-2271-8959

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• Simona Jurkovic Mlakar ,

  Contributed equally to this work with: Nicolas Waespe, Simona Jurkovic Mlakar

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, CANSEARCH Research Platform in Pediatric Oncology and Hematology, University of Geneva, Geneva, Switzerland

  https://orcid.org/0000-0002-2552-456X

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• Isabelle Dupanloup,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Swiss Institute of Bioinformatics, Lausanne, Switzerland

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• Mohamed Aziz Rezgui,

  Roles Writing – review & editing

  Affiliation Department of Pediatrics, Charles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, Montreal, QC, Canada

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• Henrique Bittencourt,

  Roles Writing – review & editing

  Affiliations Department of Pediatrics, Charles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, Montreal, QC, Canada, Department of Pediatrics, Clinical Pharmacology Unit, CHU Sainte-Justine, Montreal, QC, Canada, Faculty of Medicine, Department of Pharmacology, University of Montreal, Montreal, QC, Canada

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• Maja Krajinovic,

  Roles Data curation, Methodology, Resources, Writing – review & editing

  Affiliations Department of Pediatrics, Charles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, Montreal, QC, Canada, Department of Pediatrics, Clinical Pharmacology Unit, CHU Sainte-Justine, Montreal, QC, Canada, Faculty of Medicine, Department of Pharmacology, University of Montreal, Montreal, QC, Canada

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• Claudia E. Kuehni,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliations Institute of Social and Preventive Medicine, Childhood Cancer Research Group, University of Bern, Bern, Switzerland, Department of Pediatrics, Division of Pediatric Oncology and Hematology, University Hospital of Bern, Bern, Switzerland

  https://orcid.org/0000-0001-8957-2002

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• Tiago Nava,

  Roles Conceptualization, Writing – review & editing

  Affiliations Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, CANSEARCH Research Platform in Pediatric Oncology and Hematology, University of Geneva, Geneva, Switzerland, Department of Women, Child and Adolescent, Division of Pediatric Oncology and Hematology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland

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• Marc Ansari

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: marc.ansari@hcuge.ch

  Affiliations Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, CANSEARCH Research Platform in Pediatric Oncology and Hematology, University of Geneva, Geneva, Switzerland, Department of Women, Child and Adolescent, Division of Pediatric Oncology and Hematology, Geneva University Hospitals and University of Geneva, Geneva, Switzerland

  https://orcid.org/0000-0002-9649-6498

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