Comparison of the efficacy of second and third generation lentiviral vector transduced CAR CD19 T cells for use in the treatment of acute lymphoblastic leukemia both in vitro and in vivo models

• Piamsiri Sawaisorn ,

  Contributed equally to this work with: Piamsiri Sawaisorn, Korakot Atjanasuppat

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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• Korakot Atjanasuppat ,

  Contributed equally to this work with: Piamsiri Sawaisorn, Korakot Atjanasuppat

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – review & editing

  Affiliation Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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• Kitipong Uaesoontrachoon,

  Roles Conceptualization, Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Genepeutic Bio, Co. Ltd., Bangkok, Thailand

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• Parin Rattananon,

  Roles Conceptualization, Data curation, Investigation

  Affiliation Genepeutic Bio, Co. Ltd., Bangkok, Thailand

  https://orcid.org/0000-0002-1911-8987

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• Worapapar Treesuppharat,

  Roles Formal analysis, Investigation, Methodology, Software, Validation

  Affiliation Thammasat University Research Unit in Mechanisms of Drug Action and Molecular Imaging, Drug Discovery and Development Center, Office of Advanced Science and Technology, Thammasat University, Pathum Thani, Thailand

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• Suradej Hongeng,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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• Usanarat Anurathapan

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: usanarat.anu@mahidol.ac.th

  Affiliation Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

  https://orcid.org/0000-0002-2791-7471

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