Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

Omar Ragy; Vilma Rautemaa; Alison Smith; Paul Brenchley; Durga Kanigicherla; Patrick Hamilton

doi:10.1371/journal.pone.0281726

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Open Access

Peer-reviewed

Research Article

Can use of the serum anti-PLA₂R antibody negate the need for a renal biopsy in primary membranous nephropathy?

Omar Ragy ,

Roles Conceptualization, Formal analysis, Project administration, Writing – original draft, Writing – review & editing

* E-mail: omar.ragy@mft.nhs.uk

¶☯ These authors contributed equally to this work and considered as joint primary authorship.

Affiliations Manchester Institute of Nephrology and Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom, Wellcome Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom
⨯
Vilma Rautemaa ,

Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

¶☯ These authors contributed equally to this work and considered as joint primary authorship.

Affiliation Manchester Institute of Nephrology and Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom

https://orcid.org/0000-0003-0958-2783

⨯
Alison Smith,

Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom
⨯
Paul Brenchley,

Roles Supervision

Affiliations Wellcome Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, United Kingdom
⨯
Durga Kanigicherla,

Roles Data curation, Supervision, Visualization, Writing – review & editing

Affiliations Manchester Institute of Nephrology and Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom, Wellcome Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom
⨯
Patrick Hamilton

Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

Affiliations Manchester Institute of Nephrology and Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom, Wellcome Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, United Kingdom
⨯

Can use of the serum anti-PLA₂R antibody negate the need for a renal biopsy in primary membranous nephropathy?

Omar Ragy,
Vilma Rautemaa,
Alison Smith,
Paul Brenchley,
Durga Kanigicherla,
Patrick Hamilton

Published: February 24, 2023
https://doi.org/10.1371/journal.pone.0281726

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Enzyme-linked immunoassays
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Biopsy
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Diagnostic medicine
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Renal analysis
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Renal system
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Serum albumin
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Membrane potential
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Surgical and invasive medical procedures
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