Protocol for pragmatic randomized clinical trial to evaluate the completion of treatment of latent Mycobacterium tuberculosis infection with Isoniazid in the 300 mg formulation

• João Paulo Cola ,

  Contributed equally to this work with: João Paulo Cola, Thiago Nascimento do Prado, Ethel Leonor Noia Maciel

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

  https://orcid.org/0000-0003-4972-4686

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• Thiago Nascimento do Prado ,

  Contributed equally to this work with: João Paulo Cola, Thiago Nascimento do Prado, Ethel Leonor Noia Maciel

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

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• Bárbara Almeida Campos ,

  Roles Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

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• Bárbara Juliana Pinheiro Borges ,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

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• Bárbara Manuella Cardoso Sodré Alves ,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Pharmaceutical Sciences, Universidade de Brasília, Brasília, Distrito Federal, Brazil

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• Sonia Vivian de Jezus ,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

  https://orcid.org/0000-0002-0423-8927

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• Carolina Maia Martins Sales ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

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• Wildo Navegantes de Araújo ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Tropical Medicine, Universidade de Brasília, Brasília, Distrito Federal, Brazil

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• Noemia Urruth Leão Tavares ,

  Roles Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  ¶‡ BAC, BJPB, BMCSA, SVJ, CMMS, WNA and NULT also contributed equally to this work.

  Affiliation Postgraduate Program in Pharmaceutical Sciences, Universidade de Brasília, Brasília, Distrito Federal, Brazil

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• Ethel Leonor Noia Maciel

  Contributed equally to this work with: João Paulo Cola, Thiago Nascimento do Prado, Ethel Leonor Noia Maciel

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: ethel.maciel@gmail.com

  Affiliation Postgraduate Program in Collective Health, Laboratory of Epidemiology, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil

  https://orcid.org/0000-0003-4826-3355

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