Synaptic boutons are smaller in chandelier cell cartridges in autism

Tiffany Hong; Erin McBride; Brett D. Dufour; Carmen Falcone; Mai Doan; Stephen G. Noctor; Verónica Martínez-Cerdeño

doi:10.1371/journal.pone.0281477

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Open Access

Peer-reviewed

Research Article

Synaptic boutons are smaller in chandelier cell cartridges in autism

Tiffany Hong,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America
⨯
Erin McBride,

Roles Methodology

Affiliation Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America
⨯
Brett D. Dufour,

Roles Formal analysis

Affiliation Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America
⨯
Carmen Falcone,

Roles Methodology

Affiliation Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America

https://orcid.org/0000-0001-9892-1171

⨯
Mai Doan,

Roles Methodology

Affiliation Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America
⨯
Stephen G. Noctor,

Roles Writing – review & editing

Affiliation Department of Psychiatry and Behavioral Science, UC Davis School of Medicine, Sacramento, CA, United States of America
⨯
Verónica Martínez-Cerdeño

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: vmartinezcerdeno@ucdavis.edu

Affiliations Department of Pathology and Laboratory Medicine, Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, UC Davis School of Medicine, Sacramento, CA, United States of America, MIND Institute, UC Davis Medical Center, Sacramento, CA, United States of America

https://orcid.org/0000-0002-9613-3603

⨯

Synaptic boutons are smaller in chandelier cell cartridges in autism

Tiffany Hong,
Erin McBride,
Brett D. Dufour,
Carmen Falcone,
Mai Doan,
Stephen G. Noctor,
Verónica Martínez-Cerdeño

Published: April 25, 2023
https://doi.org/10.1371/journal.pone.0281477

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Autism
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Prefrontal cortex
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Neurons
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Axons
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Synapses
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Pyramidal cells
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Signal inhibition
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Synaptic vesicles
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