Bioengineering of a Lactococcus lactis subsp. lactis strain enhances nisin production and bioactivity

• Roxana Portieles ,

  Contributed equally to this work with: Roxana Portieles, Hongli Xu

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Hongli Xu ,

  Contributed equally to this work with: Roxana Portieles, Hongli Xu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Feng Chen,

  Roles Investigation, Validation

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Jingyao Gao,

  Roles Formal analysis, Investigation

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Lihua Du,

  Roles Investigation, Methodology, Visualization

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Xiangyou Gao,

  Roles Project administration, Supervision, Validation, Visualization

  Affiliation Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China

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• Carlos Borroto Nordelo,

  Roles Investigation, Methodology, Project administration, Resources, Supervision, Visualization

  Affiliation ‎VBS Biotec SA, Yuc., México

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• Qiulin Yue,

  Roles Data curation, Formal analysis, Investigation

  Affiliation State Key Laboratory of Biobased Material and Green Papermaking, Shandong Provincial Key Lab of Microbial Engineering, Qilu University of Technology (Shandong Academic of Science), Jinan, People’s Republic of China

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• Lin Zhao,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software

  Affiliation State Key Laboratory of Biobased Material and Green Papermaking, Shandong Provincial Key Lab of Microbial Engineering, Qilu University of Technology (Shandong Academic of Science), Jinan, People’s Republic of China

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• Nayanci Portal Gonzalez,

  Roles Investigation, Methodology, Validation

  Affiliation School of Biological Science and Technology, University of Jinan, Jinan, Shandong, People’s Republic of China

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• Ramon Santos Bermudez,

  Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization

  Affiliation School of Biological Science and Technology, University of Jinan, Jinan, Shandong, People’s Republic of China

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• Orlando Borrás-Hidalgo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: orlando@yotabio.com

  Affiliations Joint R and D Center of Biotechnology, RETDA, YOTABIO-ENGINEERING CO., LTD., Rizhao, Shandong, P.R. China, State Key Laboratory of Biobased Material and Green Papermaking, Shandong Provincial Key Lab of Microbial Engineering, Qilu University of Technology (Shandong Academic of Science), Jinan, People’s Republic of China

  https://orcid.org/0000-0002-1424-2022

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