Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell carcinoma

Ahsan Ali; Asadullah Madni; Hassan Shah; Talha Jamshaid; Nasrullah Jan; Safiullah Khan; Muhammad Muzamil Khan; Muhammad Ahmad Mahmood

doi:10.1371/journal.pone.0281004

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Open Access

Peer-reviewed

Research Article

Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell carcinoma

Ahsan Ali,

Roles Conceptualization, Writing – original draft

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Asadullah Madni ,

Roles Supervision

* E-mail: Asadullah.madni@iub.edu.pk

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

https://orcid.org/0000-0002-0388-9867

⨯
Hassan Shah,

Roles Conceptualization, Software, Writing – review & editing

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Talha Jamshaid,

Roles Supervision

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Nasrullah Jan,

Roles Software, Writing – review & editing

Affiliations Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan, Akson College of Pharmacy, Mirpur University of Science and Technology (MUST), Mirpur, AJ&K, Pakistan
⨯
Safiullah Khan,

Roles Validation, Writing – review & editing

Affiliations Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan, Cadson College of Pharmacy, Kharian, Pakistan
⨯
Muhammad Muzamil Khan,

Roles Validation

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Muhammad Ahmad Mahmood

Roles Software, Validation

Affiliation Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯

Solid lipid-based nanoparticulate system for sustained release and enhanced in-vitro cytotoxic effect of 5-fluorouracil on skin Melanoma and squamous cell carcinoma

Ahsan Ali,
Asadullah Madni,
Hassan Shah,
Talha Jamshaid,
Nasrullah Jan,
Safiullah Khan,
Muhammad Muzamil Khan,
Muhammad Ahmad Mahmood

Published: February 28, 2023
https://doi.org/10.1371/journal.pone.0281004

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