Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

• Mahvish Faisal ,

  Contributed equally to this work with: Mahvish Faisal, Jana Aid, Bekzod Nodirov

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

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• Jana Aid ,

  Contributed equally to this work with: Mahvish Faisal, Jana Aid, Bekzod Nodirov

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

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• Bekzod Nodirov ,

  Contributed equally to this work with: Mahvish Faisal, Jana Aid, Bekzod Nodirov

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

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• Benjamin Lee,

  Roles Conceptualization, Formal analysis, Methodology, Visualization

  Affiliation Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

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• Miriam A. Hickey

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: miriam.ann.hickey@ut.ee

  Affiliation Department of Pharmacology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia

  https://orcid.org/0000-0002-3363-8583

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