Reliability of species detection in 16S microbiome analysis: Comparison of five widely used pipelines and recommendations for a more standardized approach

• Andreas Hiergeist ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Andreas.Hiergeist@ukr.de

  Affiliation Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany

  https://orcid.org/0000-0002-3154-0638

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• Jean Ruelle,

  Roles Formal analysis, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation SmartGene Services SARL, Lausanne, Switzerland

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• Stefan Emler,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation SmartGene Services SARL, Lausanne, Switzerland

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• André Gessner

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  Affiliation Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany

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