Transient binding sites at the surface of haloalkane dehalogenase LinB as locations for fine-tuning enzymatic activity

Agata Raczyńska; Patryk Kapica; Katarzyna Papaj; Agnieszka Stańczak; Divine Shyntum; Patrycja Spychalska; Anna Byczek-Wyrostek; Artur Góra

doi:10.1371/journal.pone.0280776

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Open Access

Peer-reviewed

Research Article

Transient binding sites at the surface of haloalkane dehalogenase LinB as locations for fine-tuning enzymatic activity

Agata Raczyńska ,

Contributed equally to this work with: Agata Raczyńska, Patryk Kapica

Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland
⨯
Patryk Kapica ,

Contributed equally to this work with: Agata Raczyńska, Patryk Kapica

Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland
⨯
Katarzyna Papaj,

Roles Investigation, Validation, Writing – original draft

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland

https://orcid.org/0000-0001-9582-4368

⨯
Agnieszka Stańczak,

Roles Formal analysis, Investigation, Methodology, Software, Visualization

Current address: Faculty of Science, Charles University, Prague, Czech Republic; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Praha 6, Czech Republic

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland

https://orcid.org/0000-0002-5335-1387

⨯
Divine Shyntum,

Roles Validation, Writing – original draft, Writing – review & editing

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland
⨯
Patrycja Spychalska,

Roles Investigation

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland
⨯
Anna Byczek-Wyrostek,

Roles Investigation

Affiliation Biotechnology Centre, Silesian University of Technology, Gliwice, Poland
⨯
Artur Góra

Roles Conceptualization, Data curation, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: a.gora@tunnelinggroup.pl

Affiliation Tunneling Group, Biotechnology Centre, Silesian University of Technology, Gliwice, Poland

https://orcid.org/0000-0003-2530-6957

⨯

Transient binding sites at the surface of haloalkane dehalogenase LinB as locations for fine-tuning enzymatic activity

Agata Raczyńska,
Patryk Kapica,
Katarzyna Papaj,
Agnieszka Stańczak,
Divine Shyntum,
Patrycja Spychalska,
Anna Byczek-Wyrostek,
Artur Góra

Published: February 24, 2023
https://doi.org/10.1371/journal.pone.0280776

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