Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects

• Sehyun Kim,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Current address: ABL Bio Inc., Seongnam, Republic of Korea

  Affiliation Department of Neuroscience, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Amy Stockwell,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliation Department of Human Genetics, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Han Qin,

  Roles Investigation, Methodology

  Affiliation Department of Neuroscience, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Simon S. Gao,

  Roles Investigation, Resources

  Affiliation Department of Clinical Imaging, Genentech Inc., South San Francisco, California, United States of America

  https://orcid.org/0000-0002-7020-037X

  ⨯
• Meredith Sagolla,

  Roles Methodology, Resources

  Affiliation Department of Research Pathology, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Ivaylo Stoilov,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Medical Affairs Ophthalmology, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Arthur Wuster,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Current address: Department of Translational Genomics, BioMarin Pharmaceutical, San Rafael, California, United States of America

  Affiliation Department of Human Genetics, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Phillip Lai,

  Roles Investigation, Methodology

  Affiliation Early Clinical Development, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Brian L. Yaspan ,

  Contributed equally to this work with: Brian L. Yaspan, Marion Jeanne

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft

  ¶‡ BLY and MJ are joint senior authors to this work.

  Affiliation Department of Human Genetics, Genentech Inc., South San Francisco, California, United States of America

  ⨯
• Marion Jeanne

  Contributed equally to this work with: Brian L. Yaspan, Marion Jeanne

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft

  * E-mail: jeanne.marion@gene.com

  ¶‡ BLY and MJ are joint senior authors to this work.

  Affiliation Department of Neuroscience, Genentech Inc., South San Francisco, California, United States of America

  https://orcid.org/0000-0001-7334-3061

  ⨯