Social isolation is linked to classical risk factors of Alzheimer’s disease-related dementias

• Kimia Shafighi ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: kimia.shafighi@mail.mcgill.ca

  Affiliation Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada

  https://orcid.org/0000-0003-0285-5865

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• Sylvia Villeneuve,

  Roles Writing – review & editing

  Affiliations McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada, Department of Psychiatry, McGill University, Montreal, Quebec, Canada, Douglas Mental Health University Institute, Studies on Prevention of Alzheimer’s Disease (StoP-AD) Centre, Montreal, Quebec, Canada

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• Pedro Rosa Neto,

  Roles Writing – review & editing

  Affiliations Douglas Mental Health University Institute, Studies on Prevention of Alzheimer’s Disease (StoP-AD) Centre, Montreal, Quebec, Canada, Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer’s Disease Research Unit, Montreal, Canada, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l’Ouest-de-l’Île-de-Montréal, Montréal, Canada, Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Canada

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• AmanPreet Badhwar,

  Roles Writing – review & editing

  Affiliations Département de Pharmacologie et Physiologie & Institut de Génie Biomédical, Faculté de Médecine, Université de Montréal, Montréal, Canada, Centre de Recherche de l’Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada

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• Judes Poirier,

  Roles Writing – review & editing

  Affiliation Centre for Studies in the Prevention of Alzheimer’s Disease, Douglas Mental Health Institute, McGill University, Montreal, Canada

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• Vaibhav Sharma,

  Roles Writing – review & editing

  Affiliation Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada

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• Yasser Iturria Medina,

  Roles Writing – review & editing

  Affiliations McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada, Neurology and Neurosurgery Department, Montreal Neurological Institute (MNI), Faculty of Medicine, McGill University, Montreal, Canada, Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Canada

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• Patricia P. Silveira,

  Roles Writing – review & editing

  Affiliations Department of Psychiatry, McGill University, Montreal, Quebec, Canada, Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, Canada

  https://orcid.org/0000-0001-8626-2519

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• Laurette Dube,

  Roles Writing – review & editing

  Affiliation Desautels Faculty of Management, McGill Center for the Convergence of Health and Economics, McGill University, Montreal, QC, Canada

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• David Glahn,

  Roles Writing – review & editing

  Affiliations Tommy Fuss Center for Neuropsychiatric Disease Research, Department of Psychiatry, Boston Children’s Hospital, Boston, MA, United States of America, Department of Psychiatry, Harvard Medical School, Boston, MA, United States of America

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• Danilo Bzdok

  Roles Conceptualization, Supervision, Validation, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Faculty of Medicine, McGill University, Montreal, Canada, McConnell Brain Imaging Centre (BIC), MNI, Faculty of Medicine, McGill University, Montreal, Canada, School of Computer Science, McGill University, Montreal, Canada, Mila—Quebec Artificial Intelligence Institute, Montreal, Canada

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