Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning

• Chung Shing Rex Ha ,

  Contributed equally to this work with: Chung Shing Rex Ha, Martina Müller-Nurasyid

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rexha@uni-mainz.de

  Affiliations Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Medicine, Institute for Medical Information Processing, Chair of Genetic Epidemiology, Biometry, and Epidemiology (IBE), LMU Munich, Munich, Germany

  https://orcid.org/0000-0001-5238-0963

  ⨯
• Martina Müller-Nurasyid ,

  Contributed equally to this work with: Chung Shing Rex Ha, Martina Müller-Nurasyid

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Medicine, Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), LMU Munich, Munich, Germanys, Faculty of Medicine, Institute for Medical Information Processing, Pettenkofer School of Public Health Munich, Biometry, and Epidemiology (IBE), LMU Munich, Munich, Germany

  https://orcid.org/0000-0003-3793-5910

  ⨯
• Agnese Petrera,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Research Unit Protein Science and Metabolomics and Proteomics Core Facility, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Stefanie M. Hauck,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Research Unit Protein Science and Metabolomics and Proteomics Core Facility, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany

  ⨯
• Federico Marini,

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliations Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany, Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg University, Mainz, Germany

  https://orcid.org/0000-0003-3252-7758

  ⨯
• Detlef K. Bartsch,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Writing – review & editing

  Affiliation Department of Visceral-, Thoracic- and Vascular Surgery, Philipps University, Marburg, Germany

  ⨯
• Emily P. Slater ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Visceral-, Thoracic- and Vascular Surgery, Philipps University, Marburg, Germany

  ⨯
• Konstantin Strauch

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliations Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany, Institute of Genetic Epidemiology, Helmholtz Zentrum München—German Research Center for Environmental Health, Neuherberg, Germany, Faculty of Medicine, Institute for Medical Information Processing, Chair of Genetic Epidemiology, Biometry, and Epidemiology (IBE), LMU Munich, Munich, Germany

  ⨯