Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations

• Chisom Soremekun,

  Roles Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations The African Computational Genomics (TACG) Research Group, MRC/UVRI, and LSHTM, Entebbe, Uganda, Department of Immunology and Molecular Biology, College of Health Science, Makerere University, Kampala, Uganda, H3Africa Bioinformatics Network (H3ABioNet) Node, Centre for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria

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• Tafadzwa Machipisa,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa, Department of Medicine, Hatter Institute for Cardiovascular Diseases Research in Africa and Cape Heart Institute, University of Cape Town, Cape Town, South Africa, Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada, Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada, Department of Pathology and Molecular Medicine, McMaster University, Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada

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• Opeyemi Soremekun,

  Roles Formal analysis, Writing – review & editing

  Affiliations The African Computational Genomics (TACG) Research Group, MRC/UVRI, and LSHTM, Entebbe, Uganda, Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, South Africa

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• Fraser Pirie,

  Roles Writing – review & editing

  Affiliation Department of Diabetes and Endocrinology, University of KwaZulu-Natal, Durban, South Africa

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• Nashiru Oyekanmi,

  Roles Writing – review & editing

  Affiliation H3Africa Bioinformatics Network (H3ABioNet) Node, Centre for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria

  https://orcid.org/0000-0002-0796-7834

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• Ayesha A. Motala,

  Roles Writing – review & editing

  Affiliation Department of Diabetes and Endocrinology, University of KwaZulu-Natal, Durban, South Africa

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• Tinashe Chikowore,

  Roles Supervision, Validation, Writing – review & editing

  Affiliations Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, Department of Pediatrics, MRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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• Segun Fatumo

  Roles Conceptualization, Funding acquisition, Supervision, Validation, Writing – review & editing

  * E-mail: segun.fatumo@lshtm.ac.uk

  Affiliations The African Computational Genomics (TACG) Research Group, MRC/UVRI, and LSHTM, Entebbe, Uganda, H3Africa Bioinformatics Network (H3ABioNet) Node, Centre for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria, Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

  https://orcid.org/0000-0003-4525-3362

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