Curcumin’s mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study

Yangyang Wang; Guoxiu Zu; Ying Yu; Jiqin Tang; Tao Han; Chengdong Zhang

doi:10.1371/journal.pone.0280112

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Open Access

Peer-reviewed

Research Article

Curcumin’s mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study

Yangyang Wang ,

Contributed equally to this work with: Yangyang Wang, Guoxiu Zu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation College of Rehabilitation Medicine, Weifang Medical University, Weifang, China
⨯
Guoxiu Zu ,

Contributed equally to this work with: Yangyang Wang, Guoxiu Zu

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft

Affiliation Department of Traditional Chinese Medicine, Shandong University of Traditional Chinese, Jinan, China

https://orcid.org/0000-0002-7773-0568

⨯
Ying Yu,

Roles Formal analysis, Methodology, Project administration, Resources, Software

Affiliation Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China
⨯
Jiqin Tang ,

Roles Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: tangjiqin0312@163.com (JT); 60012002@sdutcm.edu.cn (TH)

Affiliation Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China

https://orcid.org/0000-0002-4644-5238

⨯
Tao Han ,

Roles Funding acquisition, Methodology, Project administration, Visualization, Writing – review & editing

* E-mail: tangjiqin0312@163.com (JT); 60012002@sdutcm.edu.cn (TH)

Affiliation Department of Traditional Chinese Medicine, Shandong University of Traditional Chinese, Jinan, China
⨯
Chengdong Zhang

Roles Data curation, Software, Visualization

Affiliation College of Rehabilitation Medicine, Weifang Medical University, Weifang, China
⨯

Curcumin’s mechanism of action against ischemic stroke: A network pharmacology and molecular dynamics study

Yangyang Wang,
Guoxiu Zu,
Ying Yu,
Jiqin Tang,
Tao Han,
Chengdong Zhang

Published: January 4, 2023
https://doi.org/10.1371/journal.pone.0280112

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