A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Xiaoxi Xu; Rajendra Kumari; Jun Zhou; Jing Chen; Binchen Mao; Jingjing Wang; Meiling Zheng; Xiaolong Tu; Xiaoyu An; Xiaobo Chen; Likun Zhang; Xiaoli Tian; Haojie Wang; Xin Dong; Zhengzheng Bao; Sheng Guo; Xuesong Ouyang; Limei Shang; Fei Wang; Xuefei Yan; Rui Zhang; Robert G. J. Vries; Hans Clevers; Qi-Xiang Li

doi:10.1371/journal.pone.0279821

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Open Access

Peer-reviewed

Research Article

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Xiaoxi Xu,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Rajendra Kumari,

Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Crown Bioscience Inc., San Diego, California, United States of America

https://orcid.org/0000-0001-8961-1681

⨯
Jun Zhou,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Jing Chen,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., San Diego, California, United States of America
⨯
Binchen Mao,

Roles Formal analysis, Methodology, Software

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Jingjing Wang,

Roles Data curation, Formal analysis, Methodology, Supervision

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Meiling Zheng,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Xiaolong Tu,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Xiaoyu An,

Roles Data curation, Formal analysis, Methodology, Supervision

Affiliation Crown Bioscience Inc., San Diego, California, United States of America
⨯
Xiaobo Chen,

Roles Conceptualization

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Likun Zhang,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Xiaoli Tian,

Roles Data curation, Formal analysis, Supervision

Affiliation Shanghai Yihao Biological Technology, Xuhui District, Shanghai, China
⨯
Haojie Wang,

Roles Data curation, Methodology, Supervision

Affiliation Suzhou NeoLogics Bioscience Co, LTD, Suzhou, China
⨯
Xin Dong,

Roles Data curation, Formal analysis, Methodology

Affiliation Suzhou NeoLogics Bioscience Co, LTD, Suzhou, China
⨯
Zhengzheng Bao,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Sheng Guo,

Roles Formal analysis, Methodology, Supervision, Visualization

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Xuesong Ouyang,

Roles Formal analysis, Supervision, Visualization

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Limei Shang,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Beijing, China
⨯
Fei Wang,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Xuefei Yan,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Rui Zhang,

Roles Data curation, Formal analysis, Methodology

Affiliation Crown Bioscience Inc., Taicang City, Jiangsu, China
⨯
Robert G. J. Vries,

Roles Methodology, Supervision, Visualization

Affiliations Hubrecht Organoid Technology (HUB), Utrecht, The Netherlands, Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, Utrecht, The Netherlands
⨯
Hans Clevers,

Roles Methodology, Supervision, Visualization

Affiliation Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, Utrecht, The Netherlands
⨯
[ ... ],
Qi-Xiang Li

Roles Conceptualization, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: hqxl@yahoo.com

Affiliation Crown Bioscience Inc., San Diego, California, United States of America

https://orcid.org/0000-0002-4673-1234

⨯
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A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Xiaoxi Xu,
Rajendra Kumari,
Jun Zhou,
Jing Chen,
Binchen Mao,
Jingjing Wang,
Meiling Zheng,
Xiaolong Tu,
Xiaoyu An,
Xiaobo Chen

Published: January 5, 2023
https://doi.org/10.1371/journal.pone.0279821

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