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Open Access
Peer-reviewed
Research Article
Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
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Dimitra Lappa ,
Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Writing – original draft
* E-mail: lappa@chalmers.se (DL); nielsenj@chalmers.se (JN)
Affiliation Department of Biology and Biological Engineering, Systems and Synthetic Biology, Chalmers University of Technology, Gothenburg, Sweden
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Abraham S. Meijnikman,
Roles Resources, Writing – review & editing
Affiliations Department of Internal and Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Internal Medicine, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Kimberly A. Krautkramer,
Roles Resources, Writing – review & editing
Affiliation Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Lisa M. Olsson,
Roles Data curation, Resources, Software
Affiliation Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Ömrüm Aydin,
Roles Resources, Writing – review & editing
Affiliations Department of Internal and Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Internal Medicine, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Anne-Sophie Van Rijswijk,
Roles Resources, Writing – review & editing
Affiliation Department of Surgery, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Yair I. Z. Acherman,
Roles Resources, Writing – review & editing
Affiliation Department of Surgery, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Maurits L. De Brauw,
Roles Resources, Writing – review & editing
Affiliation Department of Surgery, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Valentina Tremaroli,
Roles Resources, Writing – review & editing
Affiliation Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Louise E. Olofsson,
Roles Project administration, Resources, Writing – review & editing
Affiliation Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Annika Lundqvist,
Roles Resources, Writing – review & editing
Affiliation Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Siv A. Hjorth,
Roles Writing – review & editing
Affiliation Faculty of Health Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
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Boyang Ji,
Roles Writing – review & editing
Affiliation Department of Biology and Biological Engineering, Systems and Synthetic Biology, Chalmers University of Technology, Gothenburg, Sweden
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Victor E. A. Gerdes,
Roles Resources, Writing – review & editing
Affiliations Department of Internal and Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Internal Medicine, Spaarne Gasthuis, Hoofddorp, The Netherlands
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Albert K. Groen,
Roles Writing – review & editing
Affiliations Department of Internal and Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Pediatrics, Laboratory of Metabolic Diseases, University of Groningen, UMCG, Groningen, The Netherlands
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Thue W. Schwartz,
Roles Supervision, Writing – review & editing
Affiliation Faculty of Health Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
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Max Nieuwdorp,
Roles Supervision
Affiliations Department of Internal and Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Fredrik Bäckhed,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliations Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Faculty of Health Sciences, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark, Department of Clinical Physiology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden
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Jens Nielsen
Roles Conceptualization, Supervision, Writing – review & editing
* E-mail: lappa@chalmers.se (DL); nielsenj@chalmers.se (JN)
Affiliations Department of Biology and Biological Engineering, Systems and Synthetic Biology, Chalmers University of Technology, Gothenburg, Sweden, BioInnovation Institute, Copenhagen N, Denmark
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Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
- Dimitra Lappa,
- Abraham S. Meijnikman,
- Kimberly A. Krautkramer,
- Lisa M. Olsson,
- Ömrüm Aydin,
- Anne-Sophie Van Rijswijk,
- Yair I. Z. Acherman,
- Maurits L. De Brauw,
- Valentina Tremaroli,
- Louise E. Olofsson
- Published: March 2, 2023
- https://doi.org/10.1371/journal.pone.0279335