Sonodynamic therapy suppresses matrix collagen degradation in vulnerable atherosclerotic plaque by modulating caspase 3 - PEDF/HIF-1α - MMP-2/MMP-9 signaling in macrophages

• Yanfeng Tian ,

  Contributed equally to this work with: Yanfeng Tian, Siqi Sheng

  Roles Conceptualization, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Cardiology, The First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China

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• Siqi Sheng ,

  Contributed equally to this work with: Yanfeng Tian, Siqi Sheng

  Roles Methodology

  Affiliation Department of Cardiology, The First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China

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• Weiwei Gao,

  Roles Data curation

  Affiliation Department of Cardiology, The First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China

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• Jianting Yao ,

  Roles Funding acquisition, Supervision, Validation

  * E-mail: yetian6@163.com, yetian@ems.hrbmu.edu.cn (YT); yaojiantin@126.com (JY)

  Affiliation Department of Cardiology, The First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China

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• Ye Tian

  Roles Funding acquisition, Supervision, Validation, Writing – review & editing

  * E-mail: yetian6@163.com, yetian@ems.hrbmu.edu.cn (YT); yaojiantin@126.com (JY)

  Affiliations Department of Cardiology, The First Affiliated Hospital, Cardiovascular Institute, Harbin Medical University, Harbin, China, The Second Affiliated Hospital of Southern University of Science and Technology (The Third People’s Hospital of Shenzhen), Southern University of Science and Technology, Shenzhen, China

  https://orcid.org/0000-0003-3726-7270

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