HSP70 inhibitors upregulate prostaglandin E₁-induced synthesis of interleukin-6 in osteoblasts

• Gen Kuroyanagi ,

  Roles Data curation, Formal analysis, Visualization, Writing – original draft

  * E-mail: kokuryugen@yahoo.co.jp

  Affiliations Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan, Department of Rehabilitation Medicine, Nagoya City University Graduate School of Medical Science, Nagoya, Japan, Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

  https://orcid.org/0000-0002-1940-0085

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• Junko Tachi,

  Roles Data curation, Investigation

  Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Kazuhiko Fujita,

  Roles Investigation

  Affiliations Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan, Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Tetsu Kawabata,

  Roles Data curation, Investigation

  Affiliations Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan, Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Go Sakai,

  Roles Data curation, Investigation

  Affiliations Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan, Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Daiki Nakashima,

  Roles Data curation, Investigation

  Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Woo Kim,

  Roles Data curation, Investigation

  Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Kumiko Tanabe,

  Roles Methodology, Software, Supervision

  Affiliation Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Rie Matsushima-Nishiwaki,

  Roles Data curation, Methodology

  Affiliation Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Takanobu Otsuka,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Orthopedic Surgery, Nagoya City University Graduate School of Medical Science, Nagoya, Japan

  ⨯
• Hiroki Iida,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Anesthesiology and Pain Medicine, Gifu University Graduate School of Medicine, Gifu, Japan

  ⨯
• Osamu Kozawa ,

  Contributed equally to this work with: Osamu Kozawa, Haruhiko Tokuda

  Roles Conceptualization, Funding acquisition, Writing – original draft

  Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Metabolic Research, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

  ⨯
• Haruhiko Tokuda

  Contributed equally to this work with: Osamu Kozawa, Haruhiko Tokuda

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

  Affiliations Department of Pharmacology, Gifu University Graduate School of Medicine, Gifu, Japan, Department of Metabolic Research, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan, Department of Clinical Laboratory/Medical Genome Center, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

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