Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock

Adolfo Ruiz-Sanmartín; Vicent Ribas; David Suñol; Luis Chiscano-Camón; Clara Palmada; Iván Bajaña; Nieves Larrosa; Juan José González; Núria Canela; Ricard Ferrer; Juan Carlos Ruiz-Rodríguez

doi:10.1371/journal.pone.0278708

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Open Access

Peer-reviewed

Research Article

Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock

Adolfo Ruiz-Sanmartín,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Vicent Ribas,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Eurecat, Centre Tecnològic de Catalunya, Digital Health Unit, Barcelona, Spain
⨯
David Suñol,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

Affiliation Eurecat, Centre Tecnològic de Catalunya, Digital Health Unit, Barcelona, Spain

https://orcid.org/0000-0002-1421-8911

⨯
Luis Chiscano-Camón,

Roles Investigation

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Clara Palmada,

Roles Investigation

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain
⨯
Iván Bajaña,

Roles Investigation

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain
⨯
Nieves Larrosa,

Roles Investigation

Affiliations Department of Clinical Microbiology, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain, CIBERINFEC, ISCIII–CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
⨯
Juan José González,

Roles Investigation

Affiliations Department of Clinical Microbiology, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Department of Genetics and Microbiology, Universitat Autònoma de Barcelona, Barcelona, Spain, CIBERINFEC, ISCIII–CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
⨯
Núria Canela,

Roles Formal analysis, Investigation, Methodology

Affiliation Eurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences (COS), Joint Unit URV-EURECAT, Unique Scientific and Technical Infrastructures (ICTS), Reus, Spain
⨯
Ricard Ferrer,

Roles Investigation, Writing – review & editing

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Juan Carlos Ruiz-Rodríguez

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: jcruiz@vhebron.net

Affiliations Department of Intensive Care, Vall d’Hebron University Hospital, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain, Shock, Organ Dysfunction and Resuscitation (SODIR) Research Group, Vall d’Hebron Research Institute, Barcelona, Spain, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain

https://orcid.org/0000-0001-7392-8617

⨯

Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock

Adolfo Ruiz-Sanmartín,
Vicent Ribas,
David Suñol,
Luis Chiscano-Camón,
Clara Palmada,
Iván Bajaña,
Nieves Larrosa,
Juan José González,
Núria Canela,
Ricard Ferrer

Published: December 2, 2022
https://doi.org/10.1371/journal.pone.0278708

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