Synthesis, antimicrobial and molecular docking study of structural analogues of 3-((5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Saharish Khaliq; Mohsin Abbas Khan; Irshad Ahmad; Imtiaz Ahmad; Javed Ahmed; Farhat Ullah

doi:10.1371/journal.pone.0278684

Open Access

Peer-reviewed

Research Article

Synthesis, antimicrobial and molecular docking study of structural analogues of 3-((5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Saharish Khaliq ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: saharish.convent@hotmail.com (SK); lasharibloch@hotmail.com (MAK)

Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

https://orcid.org/0000-0002-0908-9721

⨯
Mohsin Abbas Khan ,

Roles Conceptualization, Methodology, Project administration, Resources

* E-mail: saharish.convent@hotmail.com (SK); lasharibloch@hotmail.com (MAK)

Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Irshad Ahmad,

Roles Conceptualization, Project administration, Resources

Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Imtiaz Ahmad,

Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – review & editing

Affiliations Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan, Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Javed Ahmed,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯
Farhat Ullah

Roles Investigation, Validation

Affiliation Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
⨯

Synthesis, antimicrobial and molecular docking study of structural analogues of 3-((5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Saharish Khaliq, …
Mohsin Abbas Khan,
Irshad Ahmad,
Imtiaz Ahmad,
Javed Ahmed,
Farhat Ullah

Published: December 27, 2022
https://doi.org/10.1371/journal.pone.0278684

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