Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China

Ruichao Li; Ansu Zhao; Xiaoyan Diao; Juhui Song; Chanjuan Wang; Yanhong Li; Xiaolan Qi; Zhizhong Guan; Ting Zhang; Yan He

doi:10.1371/journal.pone.0278680

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Open Access

Peer-reviewed

Research Article

Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China

Ruichao Li ,

Contributed equally to this work with: Ruichao Li, Ansu Zhao

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China

https://orcid.org/0000-0002-5116-9709

⨯
Ansu Zhao ,

Contributed equally to this work with: Ruichao Li, Ansu Zhao

Roles Data curation, Formal analysis

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Xiaoyan Diao,

Roles Project administration, Supervision

Affiliation Department of Cardiovascular Medicine, Affiliated Hospital of Guizhou Medical University, Guiyang, China
⨯
Juhui Song,

Roles Formal analysis

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Chanjuan Wang,

Roles Conceptualization

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Yanhong Li,

Roles Writing – review & editing

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Xiaolan Qi,

Roles Conceptualization, Supervision

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Zhizhong Guan,

Roles Conceptualization, Funding acquisition, Project administration

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Ting Zhang ,

Roles Conceptualization, Formal analysis, Writing – review & editing

* E-mail: annieheyan@gmc.edu.cn (YH); 33479161@qq.com (TZ)

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯
Yan He

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: annieheyan@gmc.edu.cn (YH); 33479161@qq.com (TZ)

Affiliation Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China
⨯

Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China

Ruichao Li,
Ansu Zhao,
Xiaoyan Diao,
Juhui Song,
Chanjuan Wang,
Yanhong Li,
Xiaolan Qi,
Zhizhong Guan,
Ting Zhang,
Yan He

Published: February 9, 2023
https://doi.org/10.1371/journal.pone.0278680

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