Gamma frequency sensory stimulation in mild probable Alzheimer’s dementia patients: Results of feasibility and pilot studies

• Diane Chan ,

  Contributed equally to this work with: Diane Chan, Ho-Jun Suk, Brennan L. Jackson, Noah P. Milman

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America

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• Ho-Jun Suk ,

  Contributed equally to this work with: Diane Chan, Ho-Jun Suk, Brennan L. Jackson, Noah P. Milman

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Brennan L. Jackson ,

  Contributed equally to this work with: Diane Chan, Ho-Jun Suk, Brennan L. Jackson, Noah P. Milman

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Noah P. Milman ,

  Contributed equally to this work with: Diane Chan, Ho-Jun Suk, Brennan L. Jackson, Noah P. Milman

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Behavioral Neuroscience, Northeastern University, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-0688-0427

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• Danielle Stark,

  Roles Investigation, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Elizabeth B. Klerman,

  Roles Data curation, Formal analysis, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-7402-3171

  ⨯
• Erin Kitchener,

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Vanesa S. Fernandez Avalos,

  Roles Data curation, Formal analysis, Methodology, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Gabrielle de Weck,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Arit Banerjee,

  Roles Investigation, Software, Visualization, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0001-6971-5846

  ⨯
• Sara D. Beach,

  Roles Data curation, Formal analysis, Software, Visualization, Writing – review & editing

  Affiliations Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0003-2144-5837

  ⨯
• Joel Blanchard,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Colton Stearns,

  Roles Investigation, Methodology, Software, Visualization, Writing – review & editing

  Affiliation Department of Computer Science, Stanford University, Stanford, California, United States of America

  ⨯
• Aaron D. Boes,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Department of Pediatrics, Neurology, & Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America

  ⨯
• Brandt Uitermarkt,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Department of Pediatrics, Neurology, & Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America

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• Phillip Gander,

  Roles Investigation, Methodology

  Affiliation Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America

  ⨯
• Matthew Howard III,

  Roles Investigation, Methodology

  Affiliations Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States of America, Neuroscience Institute, University of Iowa, Iowa City, Iowa, United States of America

  ⨯
• Eliezer J. Sternberg,

  Roles Formal analysis, Investigation, Visualization

  Affiliations Department of Neurology, Milford Regional Neurology, Milford, Massachusetts, United States of America, Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  ⨯
• Alfonso Nieto-Castanon,

  Roles Formal analysis, Visualization

  Affiliation Department of Behavioral Neuroscience, Northeastern University, Boston, Massachusetts, United States of America

  ⨯
• Sheeba Anteraper,

  Roles Formal analysis, Investigation, Visualization

  Affiliation Department of Behavioral Neuroscience, Northeastern University, Boston, Massachusetts, United States of America

  ⨯
• Susan Whitfield-Gabrieli,

  Roles Formal analysis, Investigation, Software, Visualization

  Affiliation Department of Behavioral Neuroscience, Northeastern University, Boston, Massachusetts, United States of America

  ⨯
• Emery N. Brown,

  Roles Conceptualization, Data curation, Formal analysis, Software, Visualization, Writing – review & editing

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Institute for Medical Engineering and Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Institute for Data Systems and Society, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Edward S. Boyden,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Writing – review & editing

  Affiliations Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, McGovern Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Center for Neurobiological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Koch Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America

  ⨯
• Bradford C. Dickerson,

  Roles Formal analysis, Supervision, Writing – review & editing

  Affiliations Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Harvard Medical School, Boston, Massachusetts, United States of America

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•  [ ... ],
• Li-Huei Tsai

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: lhtsai@mit.edu

  Affiliations Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0003-1262-0592

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