SARS-CoV-2 spike protein variant binding affinity to an angiotensin-converting enzyme 2 fusion glycoproteins

• Alicia M. Matthews ,

  Contributed equally to this work with: Alicia M. Matthews, Thomas G. Biel

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Current address: Department of Biology, College of Arts and Science, Case Western Reserve University, Cleveland, Ohio, United States of America

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Thomas G. Biel ,

  Contributed equally to this work with: Alicia M. Matthews, Thomas G. Biel

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Uriel Ortega-Rodriguez,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0002-1700-357X

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• Vincent M. Falkowski,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Xin Bush,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island, United States of America

  https://orcid.org/0000-0002-5568-5938

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• Talia Faison,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Hang Xie,

  Roles Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Cyrus Agarabi,

  Roles Formal analysis, Funding acquisition, Investigation, Validation, Writing – original draft, Writing – review & editing

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0002-3803-2943

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• V. Ashutosh Rao,

  Roles Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0001-6817-8049

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• Tongzhong Ju

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Tongzhong.Ju@fda.hhs.gov

  Affiliation Office of Biotechnology Products, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, United States of America

  https://orcid.org/0000-0002-4429-1976

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