Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis

• Bing Yang ,

  Contributed equally to this work with: Bing Yang, Robert B. Parker

  Roles Data curation, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  ⨯
• Robert B. Parker ,

  Contributed equally to this work with: Bing Yang, Robert B. Parker

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  ⨯
• Bernd Meibohm ,

  Roles Data curation, Methodology, Writing – review & editing

  ¶‡ BM, ZHT and AS also contributed equally to this work.

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  ⨯
• Zaid H. Temrikar ,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  ¶‡ BM, ZHT and AS also contributed equally to this work.

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  ⨯
• Ashish Srivastava ,

  Roles Data curation, Investigation, Writing – review & editing

  ¶‡ BM, ZHT and AS also contributed equally to this work.

  Affiliation Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  https://orcid.org/0000-0002-7785-6718

  ⨯
• S. Casey Laizure

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: claizure@uthsc.edu

  Affiliation Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

  https://orcid.org/0000-0002-4338-0926

  ⨯