A pyridinesulfonamide derivative FD268 suppresses cell proliferation and induces apoptosis via inhibiting PI3K pathway in acute myeloid leukemia

• Yi Chen,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Tianze Wu,

  Roles Formal analysis, Validation

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Chengbin Yang,

  Roles Resources

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Mingzhu Lu,

  Roles Validation

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Zhenxia Chen,

  Roles Writing – review & editing

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

  https://orcid.org/0000-0001-8307-4184

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• Mingli Deng,

  Roles Project administration, Resources

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Yu Jia,

  Roles Project administration

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Yongtai Yang,

  Roles Project administration

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Xiaofeng Liu,

  Roles Project administration

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

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• Hongyan Wang,

  Roles Writing – review & editing

  Affiliation Institute of Metabolism and Integrative Biology, Fudan University, and Hospital of Obstetrics and Gynecology of Fudan University, Shanghai, China

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• Yun Ling,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China, Zhuhai-Fudan Innovation Institute, Zhuhai, Guangdong, China

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• Lei Lu ,

  Roles Methodology, Resources, Writing – review & editing

  * E-mail: lulei@fudan.edu.cn (LL); ymzhou@fudan.edu.cn (YZ)

  Affiliation Institute of Metabolism and Integrative Biology, Fudan University, and Hospital of Obstetrics and Gynecology of Fudan University, Shanghai, China

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• Yaming Zhou

  Roles Conceptualization, Supervision

  * E-mail: lulei@fudan.edu.cn (LL); ymzhou@fudan.edu.cn (YZ)

  Affiliation Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Department of Chemistry, Fudan University, Shanghai, China

  https://orcid.org/0000-0003-2720-9536

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